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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 22.12
Human Site: T859 Identified Species: 32.44
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 T859 Q R W E N I A T I L E A K C A
Chimpanzee Pan troglodytes XP_518055 1227 139177 T852 Q C W E N I A T I L E A K C A
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 T859 Q R W E N I A T I L E A K C A
Dog Lupus familis XP_549061 1234 139874 T860 H R W E S I A T I L E A K C A
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 T860 Q R W E S I A T I L E A K C A
Rat Rattus norvegicus Q7M6Z5 1394 158861 E1026 Q V Q A L Q R E R E Q L Q R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 T863 Q R W D N I A T I L E A K C A
Frog Xenopus laevis Q91784 1226 138905 N861 R R W E T I S N I M E A K C A
Zebra Danio Brachydanio rerio Q58G59 1363 154819 E952 G E L T K R E E I L A K K E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 R449 N E E L E R E R V E N S K L A
Honey Bee Apis mellifera XP_395595 1064 123475 N729 K E K I N S T N T E K I K S W
Nematode Worm Caenorhab. elegans P46873 699 78760 G364 Q P G A V G V G A P A Q D A F
Sea Urchin Strong. purpuratus P46872 699 78679 I364 L R E F Q K E I E E L K K Q I
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 L708 A A M A T K R L K E L L E A R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 E699 M A T K R L K E L L E A R K S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 E593 A Q L D A L F E I S S A G D A
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 93.3 100 86.6 N.A. 93.3 6.6 N.A. N.A. 93.3 66.6 26.6 N.A. 13.3 13.3 6.6 13.3
P-Site Similarity: 100 93.3 100 93.3 N.A. 100 20 N.A. N.A. 100 86.6 26.6 N.A. 26.6 26.6 6.6 13.3
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 0 N.A. N.A. 20 N.A. 20
P-Site Similarity: 6.6 N.A. N.A. 53.3 N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 13 0 19 7 0 38 0 7 0 13 57 0 13 63 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 44 0 % C
% Asp: 0 0 0 13 0 0 0 0 0 0 0 0 7 7 0 % D
% Glu: 0 19 13 38 7 0 19 25 7 32 50 0 7 7 0 % E
% Phe: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 7 % F
% Gly: 7 0 7 0 0 7 0 7 0 0 0 0 7 0 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 44 0 7 57 0 0 7 0 0 7 % I
% Lys: 7 0 7 7 7 13 7 0 7 0 7 13 69 7 0 % K
% Leu: 7 0 13 7 7 13 0 7 7 50 13 13 0 7 0 % L
% Met: 7 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 7 0 0 0 32 0 0 13 0 0 7 0 0 0 0 % N
% Pro: 0 7 0 0 0 0 0 0 0 7 0 0 0 0 0 % P
% Gln: 44 7 7 0 7 7 0 0 0 0 7 7 7 7 7 % Q
% Arg: 7 44 0 0 7 13 13 7 7 0 0 0 7 7 7 % R
% Ser: 0 0 0 0 13 7 7 0 0 7 7 7 0 7 7 % S
% Thr: 0 0 7 7 13 0 7 38 7 0 0 0 0 0 0 % T
% Val: 0 7 0 0 7 0 7 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 44 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _